A Welsh government appeal against the blocking of its legal challenge to a post-Brexit UK trade law has failed.
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Welsh ministers claim the Internal Market Act will restrict devolved powers but permission for a High Court challenge was refused last April on the grounds of being premature.
The Court of Appeal upheld the original decision that it was too soon for a judicial review.
The Welsh government has applied for permission for a Supreme Court appeal.
A spokesperson said ministers were "disappointed with the judgement and will continue to take all possible steps to challenge the UK Internal Market Act".
The act was drawn up to set out the terms of trade between the four UK nations after the Brexit transition ended last year.
Boris Johnson's government said it wanted to avoid different regulations emerging in the UK's four nations after EU rules no longer applied.
But the Welsh Parliament opposed the law, amid claims it meant attempts to set higher food standards or environmental protection in Wales could be dragged down to a lowest common denominator in another UK nation.
Ministers have been concerned the law will restrict the Senedd's ability to pass laws on some areas which are nominally devolved.
